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The safety data is encouraging: no serious adverse events documented across 100+ preclinical studies, no organ damage, and no deaths even at doses 1,000 times typical use (Sikiric et al., 2014

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What the Research Actually Supports Both compounds have genuine preclinical literature — BPC-157's tendon-healing and angiogenesis work in rats, and Thymosin Beta-4's cell-migration and cardiac-repair research — but the evidence base has consistent limits: Nearly all studies are rodent or in-vitro models