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This leads to the formation of carbon-centered phospholipids, which then react with molecular oxygen to generate PLOO·, which can remove hydrogen from another PUFA and form phospholipid hydroperoxides (25)

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Among the main non-enzymatic antioxidants are glutathione, uric acid, bilirubin, melatonin, vitamins C and E, carotenoids, polyphenols, and trace elements such as selenium and zinc