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Furthermore, the trial failed to show any statistically significant difference in the time of removal of the immobilization device, which was the primary end point of the study [108]

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The value of GSH as an immunopharmacologic agent is that it can finetune immune response in a disease-dependent and redox state-dependent manner which differs from typical broad-effect immunosuppressive treatments (Diotallevi et al., 2017) (Figure 3)

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