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Here, we describe an Fc-engineering approach, based on three amino acid substitutions (Q311R/M428E/N434W) (REW), which improves pH-dependent human FcRn binding

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[DOI] [PubMed] [Google Scholar] 114.Smith I.C.P., DesLauriers R., Saitô H., Walter R., Garrigou-Lagrange C., McGregor H., Sarantakis D

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